Mild Traumatic Brain Injury Induces Transient, Sequential Increases in Proliferation, Neuroblasts/Immature Neurons, and Cell Survival: A Time Course Study in the Male Mouse Dentate Gyrus

Mild traumatic brain injuries (mTBIs) are prevalent worldwide. mTBIs can impair hippocampal-based functions such as memory and cause network hyperexcitability of the dentate gyrus (DG), a key entry point to hippocampal circuitry. One candidate for mediating mTBI-induced hippocampal cognitive and phy...

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Bibliographic Details
Main Authors: Lyles R. Clark, Sanghee Yun, Nana K. Acquah, Priya L. Kumar, Hannah E. Metheny, Rikley C. C. Paixao, Akivas S. Cohen, Amelia J. Eisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neuroscience
Subjects:
TBI
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.612749/full