Increased STAT1 signaling in endocrine-resistant breast cancer.

Proteomic profiling of the estrogen/tamoxifen-sensitive MCF-7 cell line and its partially sensitive (MCF-7/LCC1) and fully resistant (MCF-7/LCC9) variants was performed to identify modifiers of endocrine sensitivity in breast cancer. Analysis of the expression of 120 paired phosphorylated and non-ph...

Full description

Bibliographic Details
Main Authors: Rui Huang, Dana Faratian, Andrew H Sims, Danielle Wilson, Jeremy S Thomas, David J Harrison, Simon P Langdon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3984130?pdf=render