Multiple assays in a real-time RT-PCR SARS-CoV-2 panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak

Multiple assays in a real-time RT-PCR SARS-CoV-2 panel can mitigate the risk of loss of sensitivity by new genomic variants during the COVID-19 outbreak

Objectives: In this study, five SARS-CoV-2 PCR assay panels were evaluated against the accumulated genetic variability of the virus to assess the effect on sensitivity of the individual assays. Design or methods: As of week 21, 2020, the complete set of available SARS-CoV-2 genomes from GISAID and G...

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Bibliographic Details
Main Authors: Luis Peñarrubia, Maria Ruiz, Roberto Porco, Sonia N. Rao, Martí Juanola-Falgarona, Davide Manissero, Marta López-Fontanals, Josep Pareja
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:International Journal of Infectious Diseases
Subjects:
SARS-CoV-2
RT-PCR performance
Genomic variants
Sensitivity
Online Access:http://www.sciencedirect.com/science/article/pii/S120197122030463X

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http://www.sciencedirect.com/science/article/pii/S120197122030463X

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