Search for a platelet-activating factor receptor in the Trypanosoma cruzi proteome: a potential target for Chagas disease chemotherapy

Search for a platelet-activating factor receptor in the Trypanosoma cruzi proteome: a potential target for Chagas disease chemotherapy

Chagas disease (CD) causes the highest burden of parasitic diseases in the Western Hemisphere and is therefore a priority for drug research and development. Platelet-activating factor (PAF) causes the CD parasite Trypanosoma cruzi to differentiate, which suggests that the parasite may express PAF re...

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Bibliographic Details
Main Authors: Daniel Fábio Kawano, Vinicius Barreto da Silva, Daniel Macedo de Melo Jorge, Carlos Henrique Tomich de Paula da Silva, Ivone Carvalho
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2011-12-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
PAF
GPCR
Trypanosoma cruzi
Chagas disease
bioinformatics
proteome
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000800010&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000800010&lng=en&tlng=en

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