PR-104 a bioreductive pre-prodrug combined with gemcitabine or docetaxel in a phase Ib study of patients with advanced solid tumours

<p>Abstract</p> <p>Background</p> <p>The purpose of this phase Ib clinical trial was to determine the maximum tolerated dose (MTD) of PR-104 a bioreductive pre-prodrug given in combination with gemcitabine or docetaxel in patients with advanced solid tumours.</p>...

Full description

Bibliographic Details
Main Authors: McKeage Mark J, Jameson Michael B, Ramanathan Ramesh K, Rajendran Joseph, Gu Yongchuan, Wilson William R, Melink Teresa J, Tchekmedyian N
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/496