SHOX2 Is a Direct miR-375 Target and a Novel Epithelial-to-Mesenchymal Transition Inducer in Breast Cancer Cells

MicroRNAs have added a new dimension to our understanding of tumorigenesis and associated processes like epithelial-to-mesenchymal transition (EMT). Here, we show that miR-375 is elevated in epithelial-like breast cancer cells, and ectopic miR-375 expression suppresses EMT in mesenchymal-like breas...

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Bibliographic Details
Main Authors: Sungguan Hong, Hyangsoon Noh, Yong Teng, Jing Shao, Hina Rehmani, Han-Fei Ding, Zheng Dong, Shi-Bing Su, Huidong Shi, Jaejik Kim, Shuang Huang
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558614000293