Establishment of induced pluripotent stem cell (iPSC) line from a 75-year old patient with late onset Alzheimer's disease (LOAD)

Peripheral blood mononuclear cells (PBMCs) were collected from a clinically characterised 75-year old woman with late onset Alzheimer's disease (LOAD). The PMBCs were reprogrammed with the human OSKM transcription factors using the Sendai-virus delivery system. The transgene-free iPSC showed pl...

Full description

Bibliographic Details
Main Authors: Zsuzsanna Táncos, Eszter Varga, Eszter Kovács, András Dinnyés, Julianna Kobolák
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506116300551