Metabolic Plasticity in Chemotherapy Resistance

Resistance of cancer cells to chemotherapy is the first cause of cancer-associated death. Thus, new strategies to deal with the evasion of drug response and to improve clinical outcomes are needed. Genetic and epigenetic mechanisms associated with uncontrolled cell growth result in metabolism reprog...

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Bibliographic Details
Main Authors: Maria Andrea Desbats, Isabella Giacomini, Tommaso Prayer-Galetti, Monica Montopoli
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00281/full