Microevolution in response to transient heme-iron restriction enhances intracellular bacterial community development and persistence.

Bacterial pathogens must sense, respond and adapt to a myriad of dynamic microenvironmental stressors to survive. Adaptation is key for colonization and long-term ability to endure fluctuations in nutrient availability and inflammatory processes. We hypothesize that strains adapted to survive nutrie...

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Bibliographic Details
Main Authors: Rachael L Hardison, Alistair Harrison, Rachel M Wallace, Derek R Heimlich, Meghan E O'Bryan, Robert P Sebra, Heather W Pinkett, Sheryl S Justice, Kevin M Mason
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6205647?pdf=render