Astrocyte-Derived CCL2 is Associated with M1 Activation and Recruitment of Cultured Microglial Cells

Background/Aims: Microglia are an essential player in central nervous system inflammation. Recent studies have demonstrated that the astrocytic chemokine, CCL2, is associated with microglial activation in vivo. However, CCL2-induced microglial activation has not yet been studied in vitro. The purpos...

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Bibliographic Details
Main Authors: Mingfeng He, Hongquan Dong, Yahui Huang, Shunmei Lu, Shu Zhang, Yanning Qian, Wenjie Jin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/443040