The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in <it>Flaviviridae </it>RNA polymerases

<p>Abstract</p> <p>Background</p> <p>The <it>Flaviviridae </it>virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and thus is a validated target for antiviral drugs...

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Bibliographic Details
Main Authors: Dutartre Hélène, Bussetta Cécile, Ferron François, Canard Bruno
Format: Article
Language:English
Published: BMC 2005-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/6/255