Tubular bile duct structure mimicking bile duct morphogenesis for prospective in vitro liver metabolite recovery

Abstract Background Liver metabolites are used to diagnose disease and examine drugs in clinical pharmacokinetics. Therefore, development of an in vitro assay system that reproduces liver metabolite recovery would provide important benefits to pharmaceutical research. However, liver models have prov...

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Bibliographic Details
Main Authors: Astia Rizki-Safitri, Marie Shinohara, Minoru Tanaka, Yasuyuki Sakai
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Biological Engineering
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13036-020-0230-z