IL-6 amplifies TLR mediated cytokine and chemokine production: implications for the pathogenesis of rheumatic inflammatory diseases.

IL-6 amplifies TLR mediated cytokine and chemokine production: implications for the pathogenesis of rheumatic inflammatory diseases.

The role of Interleukin(IL)-6 in the pathogenesis of joint and systemic inflammation in rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis (s-JIA) has been clearly demonstrated. However, the mechanisms by which IL-6 contributes to the pathogenesis are not completely understood. Thi...

Full description

Bibliographic Details
Main Authors: Ivan Caiello, Gaetana Minnone, Dirk Holzinger, Thomas Vogl, Giusi Prencipe, Antonio Manzo, Fabrizio De Benedetti, Raffaele Strippoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0107886

Internet

https://doi.org/10.1371/journal.pone.0107886

Similar Items