Endothelin A receptor blocker and calcimimetic in the adenine rat model of chronic renal insufficiency

Endothelin A receptor blocker and calcimimetic in the adenine rat model of chronic renal insufficiency

Abstract Background We studied whether endothelin receptor antagonist and calcimimetic treatments influence renal damage and kidney renin-angiotensin (RA) components in adenine-induced chronic renal insufficiency (CRI). Methods Male Wistar rats (n = 80) were divided into 5 groups for 12 weeks: contr...

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Bibliographic Details
Main Authors: Suvi Törmänen, Ilkka Pörsti, Päivi Lakkisto, Ilkka Tikkanen, Onni Niemelä, Timo Paavonen, Jukka Mustonen, Arttu Eräranta
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Nephrology
Subjects:
Chronic kidney disease
Sitaxentan
Cinacalcet
Creatinine
Parathyroid hormone
Renal renin-angiotensin system
Online Access:http://link.springer.com/article/10.1186/s12882-017-0742-z

Internet

http://link.springer.com/article/10.1186/s12882-017-0742-z

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