What Is Next in This “Age” of Heme-Driven Pathology and Protection by Hemopexin? An Update and Links with Iron

What Is Next in This “Age” of Heme-Driven Pathology and Protection by Hemopexin? An Update and Links with Iron

This review provides a synopsis of the published literature over the past two years on the heme-binding protein hemopexin (HPX), with some background information on the biochemistry of the HPX system. One focus is on the mechanisms of heme-driven pathology in the context of heme and iron homeostasis...

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Bibliographic Details
Main Authors: Luis Montecinos, Jeffrey D. Eskew, Ann Smith
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pharmaceuticals
Subjects:
hemopexin
heme homeostasis
iron homeostasis
hemolysis
haptoglobin
ferroptosis
inflammation
biomarker
heme oxygenase
liver
microbiome
trauma
hemorrhage
Online Access:https://www.mdpi.com/1424-8247/12/4/144

Internet

https://www.mdpi.com/1424-8247/12/4/144

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