Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast.
<h4>Background</h4>Oxidative stress is a probable cause of aging and associated diseases. Reactive oxygen species (ROS) originate mainly from endogenous sources, namely the mitochondria.<h4>Methodology/principal findings</h4>We analyzed the effect of aerobic metabolism on oxi...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-07-01
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Series: | PLoS ONE |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18665268/?tool=EBI |