The LPS Responsiveness in BN and LEW Rats and Its Severity Are Modulated by the Liver

Differences in LPS responsiveness influence the outcome of patients with sepsis. The intensity of the response is highly variable in patients and strain dependent in rodents. However, the role of the liver for initiating the LPS response remains ill defined. We hypothesize that hepatic LPS uptake is...

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Bibliographic Details
Main Authors: Haoshu Fang, Hao Jin, Chuanfeng Hua, Anding Liu, Zichen Song, Xulin Chen, Olaf Dirsch, Uta Dahmen
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2018/6328713