Progression of biopsy-measured liver fibrosis in untreated patients with hepatitis C infection: non-Markov multistate model analysis.

Progression of biopsy-measured liver fibrosis in untreated patients with hepatitis C infection: non-Markov multistate model analysis.

Fibrosis stages from liver biopsies reflect liver damage from hepatitis C infection, but analysis is challenging due to their ordered but non-numeric nature, infrequent measurement, misclassification, and unknown infection times.We used a non-Markov multistate model, accounting for misclassification...

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Bibliographic Details
Main Authors: Peter Bacchetti, Ross Boylan, Jacquie Astemborski, Hui Shen, Shruti H Mehta, David L Thomas, Norah A Terrault, Alexander Monto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3103523?pdf=render

Internet

http://europepmc.org/articles/PMC3103523?pdf=render

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