Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobiotics

<p>Abstract</p> <p>Background</p> <p>Determination of lipophilicity as a tool for predicting pharmacokinetic molecular behavior is limited by the predictive power of available experimental models of the biomembrane. There is current interest, therefore, in models that a...

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Bibliographic Details
Main Authors: Ogbonna Udochi, Adeyemo Morenikeji, Idowu Sunday
Format: Article
Language:English
Published: BMC 2009-09-01
Series:Journal of Biological Engineering
Online Access:http://www.jbioleng.org/content/3/1/14