Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.

Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.

Lysine acetylation is a posttranslational modification that is dynamically regulated by the activity of acetyltransferases and deacetylases. The human and mouse genomes encode 18 different lysine deacetylases (KDACs) which are key regulators of many cellular processes. Identifying substrates of KDAC...

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Bibliographic Details
Main Authors: Eri Maria Sol, Sebastian A Wagner, Brian T Weinert, Amit Kumar, Hyun-Seok Kim, Chu-Xia Deng, Chunaram Choudhary
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517600?pdf=render

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http://europepmc.org/articles/PMC3517600?pdf=render

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