Inferring Pairwise Interactions from Biological Data Using Maximum-Entropy Probability Models.

Maximum entropy-based inference methods have been successfully used to infer direct interactions from biological datasets such as gene expression data or sequence ensembles. Here, we review undirected pairwise maximum-entropy probability models in two categories of data types, those with continuous...

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Bibliographic Details
Main Authors: Richard R Stein, Debora S Marks, Chris Sander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4520494?pdf=render