Beneficial effects of xenon inhalation on behavioral changes in a valproic acid-induced model of autism in rats

Beneficial effects of xenon inhalation on behavioral changes in a valproic acid-induced model of autism in rats

Abstract Background Xenon (Xe) is a noble gas that has been used for the last several decades as an anesthetic during surgery. Its antagonistic effect on glutamate subtype of NMDA (N-methyl-d-aspartate) receptors resulted in evaluation of this gas for treatment of CNS pathologies, including psychoem...

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Bibliographic Details
Main Authors: A. P. Dobrovolsky, V. R. Gedzun, V. I. Bogin, D. Ma, T. E. Ichim, Iu. A. Sukhanova, A. V. Malyshev, V. A. Dubynin
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Translational Medicine
Subjects:
Xenon
Autism
ASD
NMDA
VPA model
Behavioral testing
Online Access:https://doi.org/10.1186/s12967-019-02161-6

Internet

https://doi.org/10.1186/s12967-019-02161-6

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