Pancreatic ductal adenocarcinoma immune microenvironment and immunotherapy prospects
The tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) is non-immunogenic, which consists of the stellate cells, fibroblasts, immune cells, extracellular matrix, and some other immune suppressive molecules. This low tumor perfusion microenvironment with physical dense fibrotic stroma...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2020-03-01
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Series: | Chronic Diseases and Translational Medicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2095882X20300025 |