TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21.

TWEAK is a member of the TNF superfamily of cytokines that contribute to kidney tubulointerstitial injury. It has previously been reported that TWEAK induces transient nuclear translocation of RelA and expression of RelA-dependent cytokines in renal tubular cells. Additionally, TWEAK induced long-la...

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Bibliographic Details
Main Authors: Ana B Sanz, Maria D Sanchez-Niño, Maria C Izquierdo, Aniela Jakubowski, Pilar Justo, Luis M Blanco-Colio, Marta Ruiz-Ortega, Rafael Selgas, Jesús Egido, Alberto Ortiz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20126461/?tool=EBI