From Genetic Alterations to Tumor Microenvironment: The Ariadne’s String in Pancreatic Cancer

From Genetic Alterations to Tumor Microenvironment: The Ariadne’s String in Pancreatic Cancer

The threatening notoriety of pancreatic cancer mainly arises from its negligible early diagnosis, highly aggressive progression, failure of conventional therapeutic options and consequent very poor prognosis. The most important driver genes of pancreatic cancer are the oncogene <i>KRAS</i&g...

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Bibliographic Details
Main Authors: Chiara Bazzichetto, Fabiana Conciatori, Claudio Luchini, Francesca Simionato, Raffaela Santoro, Vanja Vaccaro, Vincenzo Corbo, Italia Falcone, Gianluigi Ferretti, Francesco Cognetti, Davide Melisi, Aldo Scarpa, Ludovica Ciuffreda, Michele Milella
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
pancreatic cancer
oncogene
tumor suppressor
signaling pathway
tumor microenvironment
targeted therapy
Online Access:https://www.mdpi.com/2073-4409/9/2/309

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https://www.mdpi.com/2073-4409/9/2/309

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