Effects of resveratrol pretreatment on endoplasmic reticulum stress and cognitive function after surgery in aged mice

Effects of resveratrol pretreatment on endoplasmic reticulum stress and cognitive function after surgery in aged mice

Abstract Background Postoperative cognitive dysfunction (POCD) seriously reduces quality of life and is associated with increased morbidity and mortality. The causes and neuropathogenesis of POCD remain largely unknown. Resveratrol, a sirtuin 1 (Sirt1) activator, is a polyphenol compound found in re...

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Bibliographic Details
Main Authors: Bei Wang, Shengjin Ge, Wanxia Xiong, Zhanggang Xue
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Anesthesiology
Subjects:
Resveratrol
Endoplasmic reticulum stress
Cognitive function
Surgery
Aged mice
Online Access:http://link.springer.com/article/10.1186/s12871-018-0606-5

Internet

http://link.springer.com/article/10.1186/s12871-018-0606-5

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