Disease Module Identification Based on Representation Learning of Complex Networks Integrated From GWAS, eQTL Summaries, and Human Interactome
The study of disease-relevant gene modules is one of the main methods to discover disease pathway and potential drug targets. Recent studies have found that most disease proteins tend to form many separate connected components and scatter across the protein-protein interaction network. However, most...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-05-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fbioe.2020.00418/full |