The Parkinson’s Disease-Associated Protein DJ-1 Protects <i>Dictyostelium</i> Cells from AMPK-Dependent Outcomes of Oxidative Stress

The Parkinson’s Disease-Associated Protein DJ-1 Protects <i>Dictyostelium</i> Cells from AMPK-Dependent Outcomes of Oxidative Stress

Mitochondrial dysfunction has been implicated in the pathology of Parkinson’s disease (PD). In <i>Dictyostelium discoideum</i>, strains with mitochondrial dysfunction present consistent, AMPK-dependent phenotypes. This provides an opportunity to investigate if the loss of function of spe...

Full description

Bibliographic Details
Main Authors: Suwei Chen, Sarah J. Annesley, Rasha A. F. Jasim, Paul R. Fisher
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
Parkinson’s disease
DJ-1
PARK7
AMPK
ROS
oxidative stress
Online Access:https://www.mdpi.com/2073-4409/10/8/1874

Internet

https://www.mdpi.com/2073-4409/10/8/1874

Similar Items