The Role of the E2F Transcription Factor Family in UV-Induced Apoptosis

The Role of the E2F Transcription Factor Family in UV-Induced Apoptosis

The E2F transcription factor family is traditionally associated with cell cycle control. However, recent data has shown that activating E2Fs (E2F1-3a) are potent activators of apoptosis. In contrast, the recently cloned inhibitory E2Fs (E2F7 and 8) appear to antagonize E2F-induced cell death. In thi...

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Bibliographic Details
Main Authors: Orla Gannon, Mehlika Hazar-Rethinam, Liliana Endo-Munoz, Nicholas Saunders
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:International Journal of Molecular Sciences
Subjects:
UV
sunburn cells
E2F
apoptosis
Online Access:http://www.mdpi.com/1422-0067/12/12/8947/

Internet

http://www.mdpi.com/1422-0067/12/12/8947/

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