Comparison of Inhibitory Activities of <i>meta</i> and <i>para</i> Substituted <i>N</i>-aryl 3-Hydroxypyridin-4-one Mannosides Towards Type 1 Fimbriated <i>E. coli</i>
In uropathogenic <i>Escherichia coli</i>, mannose-specific adhesion is mediated by the FimH adhesin located at the tip of type 1 fimbriae. Novel mannosylated <i>N</i>-aryl substituted 3-hydroxypyridin-4ones with <i>meta</i> substituents on the aryl part of the mol...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Croatian Chemical Society
2016-06-01
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Series: | Croatica Chemica Acta |
Online Access: | http://hrcak.srce.hr/file/246865 |