Comparison of Inhibitory Activities of <i>meta</i> and <i>para</i> Substituted <i>N</i>-aryl 3-Hydroxypyridin-4-one Mannosides Towards Type 1 Fimbriated <i>E. coli</i>

In uropathogenic <i>Escherichia coli</i>, mannose-specific adhesion is mediated by the FimH adhesin located at the tip of type 1 fimbriae. Novel mannosylated <i>N</i>-aryl substituted 3-hydroxypyridin-4ones with <i>meta</i> substituents on the aryl part of the mol...

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Bibliographic Details
Main Authors: Vesna Petrović Peroković, Rosana Ribić, Željka Car, Srđanka Tomić
Format: Article
Language:English
Published: Croatian Chemical Society 2016-06-01
Series:Croatica Chemica Acta
Online Access:http://hrcak.srce.hr/file/246865