Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth

Successful application of microbial community for bioproduction relies on the selection of appropriate heterotroph and phototroph partners. Here, the authors construct community metabolic models to guide strain selection and experimentally validate metabolic exchanges that sustain the heterotrophs i...

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Main Authors:	Cristal Zuñiga, Tingting Li, Michael T. Guarnieri, Jackson P. Jenkins, Chien-Ting Li, Kerem Bingol, Young-Mo Kim, Michael J. Betenbaugh, Karsten Zengler
Format:	Article
Language:	English
Published:	Nature Publishing Group 2020-07-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-020-17612-8

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spelling	doaj-064f3d9969f3489aac27c15e3982f2de2021-08-01T11:40:45ZengNature Publishing GroupNature Communications2041-17232020-07-0111111310.1038/s41467-020-17612-8Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growthCristal Zuñiga0Tingting Li1Michael T. Guarnieri2Jackson P. Jenkins3Chien-Ting Li4Kerem Bingol5Young-Mo Kim6Michael J. Betenbaugh7Karsten Zengler8Department of Pediatrics, University of CaliforniaDepartment of Chemical and Biomolecular Engineering, The Johns Hopkins UniversityNational Bioenergy Center, National Renewable Energy LaboratoryDepartment of Chemical and Biomolecular Engineering, The Johns Hopkins UniversityDepartment of Chemical and Biomolecular Engineering, The Johns Hopkins UniversityEarth and Biological Sciences Directorate, Pacific Northwest National LaboratoryEarth and Biological Sciences Directorate, Pacific Northwest National LaboratoryDepartment of Chemical and Biomolecular Engineering, The Johns Hopkins UniversityDepartment of Pediatrics, University of CaliforniaSuccessful application of microbial community for bioproduction relies on the selection of appropriate heterotroph and phototroph partners. Here, the authors construct community metabolic models to guide strain selection and experimentally validate metabolic exchanges that sustain the heterotrophs in minimal media.https://doi.org/10.1038/s41467-020-17612-8
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Cristal Zuñiga Tingting Li Michael T. Guarnieri Jackson P. Jenkins Chien-Ting Li Kerem Bingol Young-Mo Kim Michael J. Betenbaugh Karsten Zengler
spellingShingle	Cristal Zuñiga Tingting Li Michael T. Guarnieri Jackson P. Jenkins Chien-Ting Li Kerem Bingol Young-Mo Kim Michael J. Betenbaugh Karsten Zengler Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth Nature Communications
author_facet	Cristal Zuñiga Tingting Li Michael T. Guarnieri Jackson P. Jenkins Chien-Ting Li Kerem Bingol Young-Mo Kim Michael J. Betenbaugh Karsten Zengler
author_sort	Cristal Zuñiga
title	Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth
title_short	Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth
title_full	Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth
title_fullStr	Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth
title_full_unstemmed	Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth
title_sort	synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2020-07-01
description	Successful application of microbial community for bioproduction relies on the selection of appropriate heterotroph and phototroph partners. Here, the authors construct community metabolic models to guide strain selection and experimentally validate metabolic exchanges that sustain the heterotrophs in minimal media.
url	https://doi.org/10.1038/s41467-020-17612-8
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Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth

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