The Guanine Nucleotide Exchange Factor ARNO mediates the activation of ARF and phospholipase D by insulin

<p>Abstract</p> <p>Background</p> <p>Phospholipase D (PLD) is involved in many signaling pathways. In most systems, the activity of PLD is primarily regulated by the members of the ADP-Ribosylation Factor (ARF) family of GTPases, but the mechanism of activation of PLD a...

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Bibliographic Details
Main Authors: Fluharty Eric, Vasudevan Chandrasekaran, Rizzo Mark A, Rojas Raúl, Shome Kuntala, Li Hai-Sheng, Santy Lorraine C, Casanova James E, Romero Guillermo
Format: Article
Language:English
Published: BMC 2003-09-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/4/13