Skeletal Muscle O-GlcNAc Transferase Action on Global Metabolism Is Partially Mediated Through Interleukin-15

Skeletal Muscle O-GlcNAc Transferase Action on Global Metabolism Is Partially Mediated Through Interleukin-15

Besides its roles in locomotion and thermogenesis, skeletal muscle plays a significant role in global glucose metabolism and insulin sensitivity through complex nutrient sensing networks. Our previous work showed that the muscle-specific ablation of O-GlcNAc transferase (OGT) led to a lean phenotype...

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Bibliographic Details
Main Authors: Morgan D. Zumbaugh, Con-Ning Yen, Jocelyn S. Bodmer, Hao Shi, David E. Gerrard
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
O-GlcNAc signaling
interleukin-15
tissue cross-talk
insulin sensitivity
myokines
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.682052/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.682052/full

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