Neuroprotection of Strongylocentrotus nudus gangliosides against Alzheimer’s disease via regulation of neurite loss and mitochondrial apoptosis

Neuroprotection of Strongylocentrotus nudus gangliosides against Alzheimer’s disease via regulation of neurite loss and mitochondrial apoptosis

Gangliosides (GLSs), abundant in the mammalian brain, have been shown to affect neuronal plasticity and neurodegenerative diseases, especially Alzheimer’s disease. However, the biological activity and neuroprotective mechanism have not yet been established for sea urchin GLSs (SU-GLSs). Herein, we e...

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Bibliographic Details
Main Authors: Xiaoxu Wang, Suyuan Tao, Peixu Cong, Yuming Wang, Jie Xu, Changhu Xue
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Journal of Functional Foods
Subjects:
Alzheimer’s disease
Sea urchin gangliosides
Aβ secretion
Neurite loss
Cognitive deficiency
Mitochondrial apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617301470

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http://www.sciencedirect.com/science/article/pii/S1756464617301470

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