The protective effects of hydrogen sulfide on the myocardial ischemia via regulating Bmal1

The protective effects of hydrogen sulfide on the myocardial ischemia via regulating Bmal1

Background: To investigate the effect of hydrogen peroxide (H2S) on myocardial clock gene Bmal1 in ischemic cardiomyocytes. Materials & methods: Quantitative PCR (qPCR) was used to detect the expression of Bmal1 at the mRNA level in H9C2 rat cardiomyocytes. The protein expressions of Bax and...

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Bibliographic Details
Main Authors: Jiaqin Hu, Yan Xue, Kai Tang, Jing Fan, Junxi Du, Wenfu Li, Siyu Chen, Chang Liu, Wenjin Ji, Jiexian Liang, Jian Zhuang, Kun Chen
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Bmal1
H2S
Myocardial ischemia
Reactive oxygen species
PI3K/Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219329245

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http://www.sciencedirect.com/science/article/pii/S0753332219329245

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