Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish
Summary: B cells express a unique antibody protein which comprises two pairs of immunoglobulin (Ig) heavy (H) and light (L) chains. In addition to an invariable constant (C) region, IgH and IgL chains encompass a variable (V) region mediating antigen binding. This unique region stems from Ig V(D)J g...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-06-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221005836 |