Individual B cells transcribe multiple rearranged immunoglobulin light chains in teleost fish

Summary: B cells express a unique antibody protein which comprises two pairs of immunoglobulin (Ig) heavy (H) and light (L) chains. In addition to an invariable constant (C) region, IgH and IgL chains encompass a variable (V) region mediating antigen binding. This unique region stems from Ig V(D)J g...

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Bibliographic Details
Main Authors: Pedro Perdiguero, Esther Morel, Patricia Díaz-Rosales, Carolina Tafalla
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221005836