Functional dissection of HOXD cluster genes in regulation of neuroblastoma cell proliferation and differentiation.

Retinoic acid (RA) can induce growth arrest and neuronal differentiation of neuroblastoma cells and has been used in clinic for treatment of neuroblastoma. It has been reported that RA induces the expression of several HOXD genes in human neuroblastoma cell lines, but their roles in RA action are la...

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Bibliographic Details
Main Authors: Yunhong Zha, Emily Ding, Liqun Yang, Ling Mao, Xiangwei Wang, Brian A McCarthy, Shuang Huang, Han-Fei Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3413684?pdf=render