Whole-Exome Sequencing in Searching for New Variants Associated With the Development of Parkinson’s Disease

Whole-Exome Sequencing in Searching for New Variants Associated With the Development of Parkinson’s Disease

Background: Parkinson’s disease (PD) is a complex disease with its monogenic forms accounting for less than 10% of all cases. Whole-exome sequencing (WES) technology has been used successfully to find mutations in large families. However, because of the late onset of the disease, only small families...

Full description

Bibliographic Details
Main Authors: Marina V. Shulskaya, Anelya Kh. Alieva, Ivan N. Vlasov, Vladimir V. Zyrin, Ekaterina Yu. Fedotova, Natalia Yu. Abramycheva, Tatiana S. Usenko, Andrei F. Yakimovsky, Anton K. Emelyanov, Sofya N. Pchelina, Sergei N. Illarioshkin, Petr A. Slominsky, Maria I. Shadrina
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
whole-exome sequencing
NGS
variant
mutation
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00136/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2018.00136/full

Similar Items