Prediction of Treatment Response to Neoadjuvant Chemotherapy for Breast Cancer via Early Changes in Tumor Heterogeneity Captured by DCE-MRI Registration

Prediction of Treatment Response to Neoadjuvant Chemotherapy for Breast Cancer via Early Changes in Tumor Heterogeneity Captured by DCE-MRI Registration

Abstract We analyzed DCE-MR images from 132 women with locally advanced breast cancer from the I-SPY1 trial to evaluate changes of intra-tumor heterogeneity for augmenting early prediction of pathologic complete response (pCR) and recurrence-free survival (RFS) after neoadjuvant chemotherapy (NAC)....

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Bibliographic Details
Main Authors: Nariman Jahani, Eric Cohen, Meng-Kang Hsieh, Susan P. Weinstein, Lauren Pantalone, Nola Hylton, David Newitt, Christos Davatzikos, Despina Kontos
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48465-x

Internet

https://doi.org/10.1038/s41598-019-48465-x

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