Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists.

Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists.

Striatal adenosine A(2A) receptors (A(2A)Rs) are highly expressed in medium spiny neurons (MSNs) of the indirect efferent pathway, where they heteromerize with dopamine D(2) receptors (D(2)Rs). A(2A)Rs are also localized presynaptically in cortico-striatal glutamatergic terminals contacting MSNs of...

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Bibliographic Details
Main Authors: Marco Orru, Jana Bakešová, Marc Brugarolas, César Quiroz, Vahri Beaumont, Steven R Goldberg, Carme Lluís, Antoni Cortés, Rafael Franco, Vicent Casadó, Enric I Canela, Sergi Ferré
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3019225?pdf=render

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http://europepmc.org/articles/PMC3019225?pdf=render

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