Osteogenic Matrix Cell Sheets Facilitate Osteogenesis in Irradiated Rat Bone

Reconstruction of large bone defects after resection of malignant musculoskeletal tumors is a significant challenge in orthopedic surgery. Extracorporeal autogenous irradiated bone grafting is a treatment option for bone reconstruction. However, nonunion often occurs because the osteogenic capacity...

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Bibliographic Details
Main Authors: Yoshinobu Uchihara, Manabu Akahane, Takamasa Shimizu, Tomoyuki Ueha, Yusuke Morita, Shintaro Nakasaki, Tomohiko Kura, Yasuaki Tohma, Akira Kido, Kenji Kawate, Yasuhito Tanaka
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/629168