Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway

Circ_0040039 May Aggravate Intervertebral Disk Degeneration by Regulating the MiR-874-3p-ESR1 Pathway

The functional alteration of nucleus pulposus cells (NPCs) exerts a crucial role in the occurrence and progression of intervertebral disk degeneration (IDD). Circular RNAs and microRNAs (miRs) are critical regulators of NPC metabolic processes such as growth and apoptosis. In this study, bioinformat...

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Bibliographic Details
Main Authors: Yongjin Li, Xuke Wang, Haiwei Xu, Guowang Li, Zhenxin Huo, Lilong Du, Kaihui Zhang, Li Shen, Hao Li, Baoshan Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
circular RNA
ESR1
apoptosis
intervertebral disk degeneration
miR-874-3p
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.656759/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.656759/full

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