Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans

Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans

Summary: We describe therapeutic monoclonal antibodies isolated from human volunteers vaccinated with recombinant adenovirus expressing Ebola virus glycoprotein (EBOV GP) and boosted with modified vaccinia virus Ankara. Among 82 antibodies isolated from peripheral blood B cells, almost half neutrali...

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Bibliographic Details
Main Authors: Pramila Rijal, Sean C. Elias, Samara Rosendo Machado, Julie Xiao, Lisa Schimanski, Victoria O’Dowd, Terry Baker, Emily Barry, Simon C. Mendelsohn, Catherine J. Cherry, Jing Jin, Geneviève M. Labbé, Francesca R. Donnellan, Tommy Rampling, Stuart Dowall, Emma Rayner, Stephen Findlay-Wilson, Miles Carroll, Jia Guo, Xiao-Ning Xu, Kuan-Ying A. Huang, Ayato Takada, Gillian Burgess, David McMillan, Andy Popplewell, Daniel J. Lightwood, Simon J. Draper, Alain R. Townsend
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719303274

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http://www.sciencedirect.com/science/article/pii/S2211124719303274

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