CACN-1/Cactin plays a role in Wnt signaling in C. elegans.

Wnt signaling is tightly regulated during animal development and controls cell proliferation and differentiation. In C. elegans, activation of Wnt signaling alters the activity of the TCF/LEF transcription factor, POP-1, through activation of the Wnt/β-catenin or Wnt/β-catenin asymmetry pathways. In...

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Bibliographic Details
Main Authors: Melissa LaBonty, Cleo Szmygiel, Lauren E Byrnes, Samantha Hughes, Alison Woollard, Erin J Cram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4084952?pdf=render