Model to Link Cell Shape and Polarity with Organogenesis

Summary: How do flat sheets of cells form gut and neural tubes? Across systems, several mechanisms are at play: cells wedge, form actomyosin cables, or intercalate. As a result, the cell sheet bends, and the tube elongates. It is unclear to what extent each mechanism can drive tube formation on its...

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Bibliographic Details
Main Authors: Bjarke Frost Nielsen, Silas Boye Nissen, Kim Sneppen, Joachim Mathiesen, Ala Trusina
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220300134