Two to five repeated measurements per patient reduced the required sample size considerably in a randomized clinical trial for patients with inflammatory rheumatic diseases
<p>Abstract</p> <p>Background</p> <p>Patient reported outcomes are accepted as important outcome measures in rheumatology. The fluctuating symptoms in patients with rheumatic diseases have serious implications for sample size in clinical trials. We estimated the effects...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2013-02-01
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| Series: | BMC Research Notes |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1756-0500/6/37 |