Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

Homotypic CARD-CARD interaction is critical for the activation of NLRP1 inflammasome

Abstract Cytosolic inflammasomes are supramolecular complexes that are formed in response to intracellular pathogens and danger signals. However, as to date, the detailed description of a homotypic caspase recruitment domain (CARD) interaction between NLRP1 and ASC has not been presented. We found t...

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Bibliographic Details
Main Authors: Zhihao Xu, Ying Zhou, Muziying Liu, Huan Ma, Liangqi Sun, Ayesha Zahid, Yulei Chen, Rongbin Zhou, Minjie Cao, Dabao Wu, Weidong Zhao, Bofeng Li, Tengchuan Jin
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03342-8

Internet

https://doi.org/10.1038/s41419-020-03342-8

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