Alterations of 5-Hydroxymethylcytosine in Human Cancers

Prior to 2009, 5-methylcytosine (5-mC) was thought to be the only biologically significant cytosine modification in mammalian DNA. With the discovery of the TET enzymes, which convert 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), however, intense interest has emerged in determining the...

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Bibliographic Details
Main Authors: Ali Yesilkanal, Lucy A. Godley, Erika L. Moen, Christopher J. Mariani, Jozef Madzo
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Cancers
Subjects:
TET
Online Access:http://www.mdpi.com/2072-6694/5/3/786