The citrate cleavage pathway and lipogenesis in rat adipose tissue: replenishment of oxaloacetate

Fatty acid synthesis via the citrate cleavage pathway requires the continual replenishment of oxaloacetate within the mitochondria, probably by carboxylation of pyruvate.Malic enzyme, although present in adipose tissue, is completely localized in the cytoplasm and has insufficient activity to suppor...

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Bibliographic Details
Main Authors: F.J. Ballard, Richard W. Hanson
Format: Article
Language:English
Published: Elsevier 1967-03-01
Series:Journal of Lipid Research
Subjects:
rat
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520389173