MYCN: From Oncoprotein To Tumor-Associated Antigen

MYCN: From Oncoprotein To Tumor-Associated Antigen

MYCN is a well known oncogene overexpressed in different human malignancies including neuroblastoma, rhabdomyosarcoma, medulloblastoma, astrocytoma, Wilms’ tumor and small cell lung cancer. In the case of neuroblastoma (NB), MYCN amplification is an established biomarker of poor prognosis. MYCN b...

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Bibliographic Details
Main Authors: Vito ePistoia, Fabio eMorandi, Annalisa ePezzolo, Lizzia eRaffaghello, Ignazia ePrigione
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Oncology
Subjects:
Immunotherapy
Neuroblastoma
Cytotoxic T Cells
MYCN oncoprotein
Tumor antigen
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00174/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00174/full

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